Mouse Secondary Antibodies
Bio X Cell Antibody, Ly6G/Ly6C, Clone RB6-8C5, Rat, 50 MG
The RB6-8C5 monoclonal antibody reacts strongly with mouse Ly6G and weakly with mouse Ly6C (Gr-1), a 21-25 kDa GPI-anchored cell surface protein. Ly6G is expressed by various myeloid lineage cells, including monocytes, macrophages, granulocytes, and neutrophils, serving as a marker for mature granulocytes and peripheral neutrophils. This antibody inhibits the binding of 1A8, which specifically reacts with mouse Ly6G.
- Endotoxin ≤0.5 EU/mg (≤0.0005 EU/µg)
- Aggregation <5%
- Purity ≥95%
- Sterility by 0.2 µm filtration
- Host species: Rat
- Isotype: Rat IgG2b, κ
- Purification by protein G
- Formulation in PBS, pH 7.0, without stabilizers or preservatives
- Store at 4°C, do not freeze
Biolegend PerCP/FireTM 780 anti-mouse CD
PerCP/Fire™ 780 anti-mouse CD152 [UC10-4B9]; Isotype: Armenian Hamster IgG; Reactivity: Mouse; Apps: FC; Size: 25 μg
Biolegend Alexa FluorR 488 anti-mouse CD
Alexa Fluor 488 anti-mouse CD326 (Ep-CAM) [W20119E]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC, IHC-F; Size: 25 μg
Cayman Chemical Farnsyl ThIosalcylc ACD A 10mg
An inhibitor of Ras-mediated signaling that inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM, respectively
Cayman Chemical Farnsyl ThIosalcylc ACD A 50mg
An inhibitor of Ras-mediated signaling that inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM, respectively
Cayman Chemical a-GunIdInoglutarIc AcId 100mg
A linear mixed-type inhibitor of nNOS having a Ki value of 2.69 µM; normally present in small quantities in the cerebral cortex of cats with increased levels following seizure
Cayman Chemical ANTIBODY 15 S-HpEDE 250ug
15(S)-HpEDE is a monohydroperoxy PUFA produced by the action of 15-LO on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).
Cayman Chemical PIfIthrIn-a 10mg
An inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis, preventing p53-mediated apoptosis by cytotoxic compounds in C8 cells at 10 μM and in human umbilical vein endothelial cells at 30 μM
Cayman Chemical MK-2206hydrochlorIde 1mg
An orally active, allosteric Akt inhibitor (IC50s = 5, 12, and 65 nM for Akt1, 2, and 3, respectively); inhibits cell proliferation of human cancer cell lines synergistically in combination with other topoisomerase inhibitors, antimetabolites, antimicrotubule agents, DNA cross-linkers or growth factor inhibitors
Cayman Chemical Acorus calamus a-asron 5g
A component of certain essential oils used in traditional Chinese herbal medicine; carcinogenic, neuroprotective, and radioprotective in mice when given at 50 mg/kg; inhibits HMG-CoA reductase (IC50 = 3 mM); inhibits CYP2D6 and CYP3A4 (IC50 = 55.2 and 65.2 μg/ml, respectively)
Biolegend Spark PLUS B550TM anti-mouse C
Spark PLUS B550™ anti-mouse CD25 [PC61]; Isotype: Rat IgG1, λ; Reactivity: Mouse; Apps: FC; Size: 25 μg
Bio X Cell Anti-Mouse Ly6G/Ly6C Antibody, RB6-8C5, Unconjugated, 100 MG
The RB6-8C5 monoclonal antibody targets mouse Ly6G and Ly6C (Gr-1), cell surface proteins in the myeloid lineage. Ly6G is a key marker for mature granulocytes and peripheral neutrophils, and the antibody has been shown to inhibit 1A8 antibody binding, which specifically reacts with mouse Ly6G.
- Reacts with mouse Ly6G and Ly6C
- Host species: rat
- Isotype: IgG2b, κ
- Immunogen: mouse granulocytes
- Formulation: PBS, pH 7.0, contains no stabilizers or preservatives
- Endotoxin: ≤0.5 EU/mg; Purity: ≥95%
- Purification: Protein G
- Applications: in vivo depletion of Gr-1+ myeloid cells, flow cytometry, immunohistochemistry
Biotium Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL
This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluores
Biotium C1QB / Complement C1q B-Chain(C1QB/2961), CF488A conjugate, 0.1mg/mL
Complement C1q B Chain (C1qb) is a subunit of C1q. C1q is composed of 6 polypeptide chains each of C1qa, C1qb, and C1qc. C1q is a component of the classical complement pathway, and thereby plays an important role in the immune response. Each C1q subunit contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets,